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In the roaming hills of the Appalachian Mountains rests a medical oddity that is so unusual that it at first seems like a hoax. Dating back to the early 1800s, a seemingly isolated family in eastern Kentucky started producing children who were blue.
As a result of a coincidental meeting of recessive genes, intermarriage and inbreeding, members of the Fugate family were born with a rare condition that made them visibly discoloured. The mystery behind the picture of the Fugates, which has been baffling people for years, appears to have finally been solved.
It began when Fugate, a French orphan, settled on the banks of eastern Kentucky's Troublesome Creek to claim a land grant. He married a red-haired American named Elizabeth Smith - who had a very pale complexion. The couple had no way of knowing that their union would form a genetic mutation that resulted in their descendants being born with blue skin.
Looking at the portrait of the family today, they look as if they have been either Photoshopped or made up to mimic the Smurfs, but science proves that the condition is in fact real.
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